Mapping microbes that influence women’s health

In the lab of Melissa Herbst-Kralovetz, professor of basic medical sciences and director of the Women’s Health Research Program at the University of Arizona College of Medicine - Phoenix, researchers focus on improving women’s health through microbiome research. Their goal is to understand how bacteria in the uterus may play a role in conditions like endometrial cancer, which affects the inner lining of the uterus and is one of the most common cancers in women. 

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Phoenix KEYS intern Matthew Hawkins (he/him) worked with postdoctoral researcher Nicole Jimenez to study a little-known bacterium called Schaalia turicensis. This microbe has been linked to infections elsewhere in the body, but its role in the uterus is still a mystery. Hawkins helped grow the bacteria in the lab and compare its genetic code to similar strains.  

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“Seeing his enthusiasm for science and the meaningful conversations he sparked, even with his own family, reminds me why I love mentoring,” said Jimenez. “This experience shows how early exposure to science can light a lifelong spark.” 

Herbst-Kralovetz agrees. “I was mentored as an undergrad, and it changed my entire career path. That’s why I want to pay it forward—supporting young scientists like Matthew is one of the most rewarding parts of what we do.” 

By studying its DNA, Hawkins hopes to help determine whether S. turicensis may influence the development of uterine disease. 

“I’m passionate about science because I want to help people, and I’ve learned just how big the gaps are in women’s health research,” said Hawkins. “My dream is to become a cardiothoracic surgeon, but no matter where I end up, I want to keep learning and collaborating to make a difference.” 

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Take a closer look at how KEYS interns are helping advance real-world research across Arizona.